It is well-known that the introduction of fluorine atom(s) into the organic frameworks significantly alters their chemical and biological properties. Several methods have been developed to introduce trifluoromethyl (CF₃) or difluoromethyl (CHF₂) moiety via the nucleophilic, electrophilic and radical intermediates. However, compared with trifluoro- and difluoromethylation reactions, monofluoromethylation is still limited. This review focuses on recent achievements in nucleophilic monofluoromethylation using carbenoid chemistry.